Commentary in Nature

15 November 2024

A study by Lesuis et al. (2025), published in Cell, has shown that stress disrupts memory formation. This makes it difficult to distinguish between neutral and fearful events, which may explain why stress causes people to feel threatened in safe environments. This kind of research forms the basis for future treatments for conditions like PTSD and anxiety disorders. An interdisciplinary team was involved in the research, and Mario van der Stelt, project leader at iCNS, was a co-author of the publication.

“This paper is really a tour de force,” said Ryuichi Shigemoto, a neuroscientist at the Institute of Science and Technology Austria in Klosterneuburg. “They used so many different methods and techniques to prove this long pathway.”

Read the full commentary on the publication: https://doi.org/10.1038/d41586-024-03724-4